In his winning essay in SCI Scotland’s Postgraduate Researcher competition, Alexander Triccas, postgraduate chemistry researcher at the University of Edinburgh, explains how the tiny shells produced by marine algae protect our natural environment.
Each year, SCI’s Scotland Regional Group runs the Scotland Postgraduate Researcher Competition to celebrate the work of research students working in scientific research in Scottish universities.
This year, four students produced outstanding essays. In the fourth of this year’s winning essays, Alexander Triccas explained how coccoliths provide a valuable carbon store and could play a key role in keeping our bones healthy.
Although humans can engineer complex and eye-catching structures that help us navigate through our daily lives, they are nowhere close to the design and functionality of natural materials.
These mineral structures are specifically grown to provide support, protection, or food for many organisms. Humans would not exist without them. Indeed, our bones and teeth are made of calcium phosphate. But when grown in a lab, calcium phosphate forms as simple rectangular crystals, which is vastly different to how our bones and teeth look.
This is because our bodies use organic molecules to precisely control how minerals grow, producing materials that can fulfil very specific tasks. Biominerals can even be produced inside single cells. Coral reefs are held together by calcium carbonate minerals made by marine invertebrates. Elsewhere in the ocean, carbonate shells produced by small algae cells are buried on the ocean floor, over time forming the chalk rocks that make up coastal landmarks such as the White Cliffs of Dover.
Advances in microscopy are shedding new light on the composition of coccoliths.
This process is incredibly important to the environment. It takes carbon dissolved in seawater, turns it into solid material, then stores it at the bottom of the ocean. It is concerning then that we don’t know how ocean acidification and rising CO2 levels will affect coccoliths, the name given to these carbonate shells.
>> SCI’s Scotland Group connects scientists working in industry and academia throughout Scotland. Join today!
We’re still unsure how coccoliths are produced, particularly how organic molecules are used to give them their unique shape. Proteins and sugars decide where and when the first carbonate mineral forms; then the growth of the coccolith is controlled by sugar molecules.
But how exactly do these organic molecules control the mineral that is produced? We struggle to answer this question because we don’t know how the composition of the coccolith changes as the structure grows.
Our research focuses on imaging coccoliths in an attempt to observe these changes. We used a technique called X-ray ptychography to map coccolith composition over the course of its formation. This revealed that coccoliths are not entirely made of calcium carbonate, instead having a hybrid structure containing mineral and organic molecules. But this isn’t all.
We revealed that the composition of the coccolith changes during its growth. We think this could represent a transition from a disordered liquid-like state to an ordered crystalline state. While this is common in other biomineral-produced organisms like corals, no evidence of this transition has been reported in coccolith formation before.
>> Read Rebecca Stevens’ winning essay on PROTAC synthesis.
This is incredibly important because it tells us how the cell is controlling the first calcium carbonate mineral that forms. The transition enables the cell to control exactly how it wants the mineral to form, meaning coccoliths can be made faster.
It might also lessen the impact that more acidic seawater has on mineral formation. This could mean coccoliths will not be affected by ocean acidification as much as expected, which is good for the planet’s long-term carbon stores.
However, this is only a prediction. Improvements to the microscopes used to analyse coccoliths will help us know if the transition occurs. Electron and X-ray microscopes are extremely useful in industry – from drug research and medical imaging, to data storage and materials analysis – but their use in these fields is still relatively novel.
Coccolith analysis could give us a better idea of how bones are produced.
Most advancements in instrumental procedures are done in academic research. Our work, therefore, helps us understand the benefits and limits microscopes may have, making them more suitable for industrial use.
Bone research also relies heavily on these microscopes. Our findings could be important in understanding how bones are produced, benefiting not only pharmaceutical and medical industries, but also improving human healthcare by providing better treatments to patients.
From luminescent polymer nanoparticles that improve rural healthcare to compostable plastic packaging, Dr Zachary Hudson and his research group at the University of British Columbia are developing solutions to pressing issues.
For those of us who live in cities, we take easy access to hospitals for granted, but what about those in remote areas? What if there were an easier way to diagnose diseases and improve healthcare for those in secluded rural areas?
Luminescent dyes used to make fluorescent Pdots.
Well, Dr Zachary Hudson and his group at the University of British Columbia (UBC) in Canada are developing luminescent polymer nanoparticles that could provide portable, low-cost tools for bio-imaging and analysis in rural areas. These nanoparticles are so bright that they can be detected by smartphone, helping clinicians quantify chemical substances of interest such as cancer cells.
Dr Hudson’s work spans other areas too, including working with industry to develop compostable plastics and ongoing research in opto-electronics. His creativity in applied polymer science was recognised recently with the 8th Polymer International-IUPAC award, organised by SCI, the Editorial Board of Polymer International, and IUPAC (International Union of Pure and Applied Chemistry).
We caught up with Zac to ask about these luminous Pdots, compostable plastics, and how it felt to be recognised by his peers.
Dr Zachary Hudson
Tell us about the nanoparticle and remote diagnostic technologies you are developing to boost rural healthcare.
Our group is working with Professor Russ Algar, an analytical chemist at UBC, to develop fluorescent nanoparticles that are bright enough to be detected by a handheld smartphone camera.
The concept is to design nanoparticles that can quantify biological analytes of interest, such as cancer cells or enzymes, and provide a signal that a smartphone can measure. In this way, we hope to create portable, low-cost tools for bioanalysis for use in remote or low-income regions.
Why is the capacity to conduct remote diagnostics so important for those in remote areas?
Coming from Vancouver, I have ready access to sophisticated lab facilities and hospitals that are only a short distance from where I live. This gives me access to some of the world’s most advanced techniques in molecular medicine with relative ease.
For most of the world’s population, however, geography or resources limit their access to these advanced tools that can have a real, positive impact on human health. Expanding access to molecular diagnostic technologies can help more people get the diagnosis they need without a dedicated lab.
How did the ideas for the Pdots come about?
We became interested in Pdots due to Professor Algar’s groundbreaking work using quantum dots for smartphone-based bioanalysis. We learned that by tapping into the versatility of polymer chemistry, we could create polymer nanoparticles, or Pdots, that combined many advanced functions into a single particle.
>> From Covid-19 to the two World Wars, how has adversity shaped innovation? We took a closer look.
How have you worked with other partners to turn these ideas into a reality?
We are currently planning a major initiative with rural health organisations in British Columbia to help move these tools toward practical use. Stay tuned for more info!
You’ve also worked with local industry to reduce the use of single-use plastics. How have you gone about this?
There has been a major push in Canada to reduce the consumption of single-use plastics, and many companies are currently developing new products to respond to this need. Our lab has worked with local industry to formulate and test compostable plastics that can act as substitutes for petroleum-based plastics in consumer packaging.
The Nexe Pod, a fully compostable, plant-based coffee pod created by NEXE Innovations, with Zac as Chief Scientific Officer, received a $1m funding grant from the Canadian government in 2021.
You’ve helped develop compostable materials. How tricky is this from both a material and an environmental perspective?
Compostable plastics are challenging for a few reasons: the demand for them is skyrocketing, so robust supply chains are needed to help companies get away from petroleum feedstocks. The regulatory framework around compostable plastics also varies widely by country, which poses challenges for international commercialisation.
Finally, most machinery for the high-speed manufacturing of plastic packaging is highly optimised for petroleum-based plastics, so new equipment and techniques that are suitable for processing compostable plastics need to be developed alongside the plastics themselves.
>> Do you work in pharmaceutical development? Check out our upcoming events.
What’s next for these innovations, and are you working on anything else interesting?
I've spent most of my career working on light-emitting materials for display technologies and bioimaging, and we’ve recently learned that many of these same materials make useful photocatalysts with applications in the pharmaceutical industry.
We recently partnered with Bristol Myers Squibb to develop all-organic photocatalysts with performance on par with some of the expensive iridium-based catalysts that industry is currently using. I'm looking forward to developing this area further.
What was it like to win the 8th Polymer International-IUPAC award for Creativity in Applied Polymer Science?
It was a great feeling to have our group’s work recognised by the international polymer community. The award lecture at the IUPAC conference also gave us the perfect venue to highlight some of the research directions I’m most excited about in the years ahead.
In her winning essay in SCI Scotland’s Postgraduate Researcher competition, Marina Economidou, first year PhD Student at GSK/The University of Strathclyde, talks about palladium recovery.
Each year, SCI’s Scotland Regional Group runs the Scotland Postgraduate Researcher Competition to celebrate the work of research students working in scientific research in Scottish universities.
This year, four students produced outstanding essays in which they describe their research projects and the need for them. In the second of this year’s winning essays, Marina Economidou explains the need for palladium recovery and making it more efficient.
Pictured above: Marina Economidou
U-Pd-ating the workflows for metal removal in industrial processes
Palladium-catalysed reactions have great utility in the pharmaceutical industry as they offer an easy way to access important functional motifs in molecules through the formation of carbon-carbon or carbon-hetero-atom bonds.
The superior performance of such reactions over classical methodologies is evident in modern drug syntheses, where Buchwald-Hartwig, Negishi or Suzuki cross-coupling reactions are frequently employed.
However, the demand for efficient methods of palladium recovery runs parallel to the increased use of catalysts in synthesis. The interest in metal extraction can be attributed to several reasons.
Cross-coupling steps are usually situated late in the synthetic route, resulting in metal residues in the final product. In addition to possessing intrinsic toxicity, elemental impurities can have an unfavourable impact on downstream chemistry.Hence, their limit must be below the threshold set by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH).
The need for palladium recovery
However, the importance of palladium recovery does not only arise from the need to meet regulatory criteria. The volatility of palladium supply as a result of geopolitical instabilities has been a focus of attention this year, with Russia producing up to 30% of the global supply and prices reaching an all-time high of £81,179 per kilogramme.
Therefore, aside from the need to remove metals from the product for regulatory reasons, there is a desire to recover metals from waste streams as effectively as possible due to their finite nature and high costs.
The sustainability benefits of recovery for circular use are an additional incentive for an efficient extraction process, as catalysts can be regenerated when metal is returned to suppliers.
The increasing pressure for greener processes and more ambitious sustainability goals – such as GlaxoSmithKline’s environmental sustainability target of net zero impact on climate by 2030 – also contribute to the need for further refinement of working practices.
>> SCI's Scotland Group connects scientists working in industry and academia throughout Scotland.
Palladium has many uses including in catalytic converters, surgical instruments, and dental fillings.
Improving extraction processes
It is essential to have well-controlled and reproducible processes for pharmaceutical production, as redevelopment requires further laboratory work and additional time and resources.
With several industry reports on the inconsistent removal of palladium following catalytic synthetic steps, there seems to be a knowledge gap as to which factors affect the efficiency of extraction and why there can be significant differences between laboratory and plant conditions.
The focus of my PhD is investigating the speciation of palladium in solution in the presence of pharmaceutically relevant molecules, to offer an insight into the efficiency of metal extraction at the end of processes.
By understanding the oxidation state and coordinative saturation of the palladium species formed in the presence of different ligands, a better relationship could be established between the observed performance of metal extraction processes under inert and non-inert conditions.
With the wide breadth of ligands and extractants that are now commercially available for cross-coupling reactions, my ambition is to generate a workflow for smart condition selection that not only achieves selective metal recovery, but is scalable and can be transferred to plant with consistent performance.
The cost and preciousness of metal catalysts are both factors that prohibit their one-time use in processes. Understanding how palladium can be extracted and recovered in an efficient manner will not only deliver reliable processes that meet the demands of the market in the production of goods, it will also lead to economic and environmental benefits.
>> Read Angus McLuskie’s winning essay on replacing toxic feedstocks.
>> Our Careers for Chemistry Postdocs series explores the different career paths taken by chemistry graduates.
Paulina Quintanilla has developed a clever way to maximise the froth flotation technology used to extract more valuable minerals from rocks. The SCI Scholar and Poster Competition winner chatted to us about her process and how it could make mineral processing more efficient.
How would you describe your froth flotation technology in simple terms?
Froth flotation is the most widely used technology to separate valuable mineral particles from waste rock. The process is carried out in stirred tanks in which chemical reagents and air are added. Some of these reagents, called collectors, make the valuable mineral particles hydrophobic, which means that they repel water.
Consequently, the valuable mineral particles attach to the air bubbles, covering them and generating bubble-particle aggregates. The bubble-particle aggregates rise to the top of the tank, forming a froth that overflows as a mineral-rich concentrate, while the waste rock leaves from the bottom of the tank as tailings.
Froth flotation is also relevant in several other industrial applications, such as water treatment and paper de-inking.
Schematic of the froth flotation process. Image by @AMPRG_Imperial.
How would you describe your froth flotation technology in simple terms?
This research focuses on optimising the froth flotation process using a control strategy called model predictive control. To this end, mathematical models were developed to represent the phenomena inside a flotation tank. These models are then used to ‘predict the future’ so that decisions can be taken now (we can control the process) to improve the froth flotation performance.
Model predictive control is a powerful optimisation strategy that has been widely used in other processes, including in the petrochemical industry, but it is still very new in the mineral processing industry.
One of the main advantages of this research is that the models are physics-based. This means that they were developed from the fundamental physics of the process rather than from data, which makes them useful under any operating conditions, for any flotation tank size. This is particularly interesting for application in the large flotation tanks used on an industrial scale.
How could this work benefit industry and make processing more efficient?
Building clean technologies for the transition to 100% green energy is creating a massive demand for a range of minerals. For example, copper mines would have to ramp up production considerably to satisfy the extra 7% predicted demand. Meeting that demand, however, is becoming more and more challenging as ores are becoming lower grade, deeper, and more complex.
This implies that there is an urgent need to optimise current processes to extract the necessary minerals and metals more sustainably and efficiently. As froth flotation is a large-scale process, even small improvements in the separation efficiency would translate into important increments in production.
Overflowing froth seen from the top of an industrial-scale tank. Image by @AMPRG_Imperial.What is the potential of this work in terms of copper recovery?
We demonstrated that improvements of between 8 to 22% in metal recovery were achieved by implementing a model predictive control strategy at the laboratory scale, revealing an untapped potential for implementation at an industrial scale. This research could serve as a promising next step for the mining industry to meet future metal and mineral demands by extracting more metal for the same amount of resources, such as water, energy, and chemicals.
>> Interested to find out more about SCI Scholarships?
Your flotation tanks are actually based in Chile. How do you operate them remotely?
I am currently implementing an online model predictive control strategy in a laboratory-scale flotation bank in Chile. I monitor and control this experimental rig from home, in the UK.
The experimental rig was automated in such a way that all the instruments (e.g. air flow meters, controllers, pumps, etc.) are connected to a module called ‘Programmable Logic Controller’. This module is then connected to a workstation computer, which I access from my laptop in the UK.
The Programmable Logic Controller allows me to obtain measurements in real-time and control the system. In this case, the measurements are used to update the mathematical models, while the system is controlled by changing the ‘revolutions per minute’ of the pumps (to change the pulp levels) and/or moving the air valves (to change the airflow rates).
Experimental campaign in 2018 – aerial view of a 300m³ froth flotation tank. Image by @AMPRG_Imperial.
Could this process be used to extract other materials? If so, which ones?
While froth flotation is widely used to separate sulphide minerals of copper, it is also used to separate other sulphides, such as those containing lead, zinc, and molybdenum.
You won an SCI Scholarship. How did you use the funds you received to develop your research?
I used the generous SCI scholarship to partially fund a two-month visit to the laboratory in Chile. I set up new connections for remote control by installing new instrumentation to make it even more automated, and I carried out preliminary online control experiments. Since then, all the control experiments have been carried out from my laptop at home.
I also used the scholarship to fund my participation in several conferences, including one in person in Athens, Greece, in 2021. I have participated in Scholar Days in 2020 and 2021, in which I presented advances in my PhD research to a wide audience. This year, I presented my PhD research results at SCI headquarters for the first time and participated in the Poster Showcase, where I won first place.
Paulina presenting at the SCI Scholars' Showcase in July 2022. Image: SCI/Andrew Lunn
What are your future plans for this innovative technology (and other potential research)?
I plan to keep up the momentum of researching froth flotation optimisation, as I believe that there is still a long way to go for improvement, particularly at an industrial scale. Model predictive control has not been widely explored within the mineral processing industry despite the fact that it has shown great potential. There is still a gap between academia and industry that should be bridged, sooner rather than later, to improve the performance of the process.
Apart from the model predictive control strategy using physics-based models (including the one I have investigated during my PhD research), many other control strategies show great potential to be tested and implemented at an industrial scale.
This is particularly applicable in mineral processing plants, as most of them collect a huge amount of data that could serve as valuable inputs for further improvement and optimisation, using novel engineering tools such as artificial intelligence and digital twins.
Paulina is part of the Advanced Mineral Processing Research Group at Imperial College London, whose research includes fluid dynamics of flotation tanks and multi-criteria decision-making for sustainable mining and mineral processing.
At COP26, Nikita Patel co-hosted the Next-Gen debate, where an inspiring group of young people discussed how chemistry is tackling climate change. The PhD student at Queen Mary University of London shares her experience.
While the United Nations Climate Change Conference (COP26) may be over, there is still plenty to be done in the fight against climate change. We’ve seen what can be achieved when we work together and no doubt science will play a key role.
On Thursday 4 November, I had the privilege of co-hosting the Countdown to Planet Zero Next-Gen debate organised by SCI to showcase the work being carried out by our young and innovative scientists to tackle climate change. It was a real pleasure to share the stage and hear from some great scientists, exploring the themes Fuels of the Future, Turning Waste into Gold and Engineering Nature. The event gave the audience the opportunity to question and challenge the panel members on their climate change solutions.
Panel L-R: Dominic Smith, Natasha Boulding, Clare Rodseth, Jake Coole, Nikita Patel, Oliver Ring (Brett Parkinson joined virtually).
While I was feeling nervous about my hosting duties, I was very excited at the same time as I knew how important it was to educate the audience, whether they were members of the public or aspiring scientists, on how science is crucial in battling the climate emergency.
An important part of my role as a host was to ensure the incoming questions and comments were understood by all, given the mixed audience attending. This highlighted how essential good science communication is to prevent misunderstandings and the spread of misinformation.
It was brilliant to see how engaged the audience were from the flurry of questions that came in during the session, so much so that we didn’t manage to get through all of them! There were a wide variety of questions aimed at particular panellists but also towards the panel as a whole. It was thought-provoking to hear how scientists from different backgrounds offered their own perspectives on the same topic.
4 November was also Energy Day at COP26 and the atmosphere was buzzing! I learnt a lot from attending the Green Zone, not only from our panellists but from all the exhibitors present too. I appreciate the small, individual actions we can each take that will make a difference but also the need to work together to achieve the common goal of fighting climate change. It was clear to see how science and business go hand in hand to provide solutions to society and how interdisciplinary collaboration is key.
The result of our poll question: ‘Do you think that science is pivotal in providing climate change solutions?’ spoke for itself, with a resounding yes from 100% of the audience participants! This was a very positive outcome and showed that it is not all doom and gloom when it comes to discussing the climate crisis.
On a personal level, I'm going to continue implementing some simple changes like using public transport more, eating more vegan food and flying less and aim to keep the discussion going with my peers as the climate emergency is far from over.
SCI team, panellists and hosts.
I hope the youth panel event has inspired the next generation of scientists and showcased some of the exciting work that is going on behind the scenes which people may not realise and ultimately, that there is hope in science.
>> To rewatch the event, the recording is available on the COP26 YouTube channel: Countdown to Planet Zero Combating climate change with chemistry | #COP26, and on our Climate Change Solutions hub.
>> Want to read more about the technologies discussed by our panel? Read our event review: https://www.soci.org/blog/2021/11/2021-11-05-cop26-review.
A group of inspiring young scientists took centre stage at COP26 on 4 November to show how the next generation of chemists is finding tangible climate change solutions.
In a day dominated by what countries pledged to stop doing at COP26, such as pursuing coal power and financing fossil fuel projects overseas, it was refreshing to learn about low-carbon technologies and the young people driving their development. At the Next Gen forum, we heard from an array of young chemists, all associated with SCI, who are at the sharp edge of this change.
We heard from Brett Parkinson, Senior Engineer of Low Carbon Fuels and Energy Technologist at C-Zero, who is working on commercialising a way to decarbonise natural gas. The California-based company’s technology converts the natural gas into hydrogen and solid carbon to provide a clean energy source while sequestering the carbon; and the aim is to have this process up and running next year.
Natasha Boulding is building towards Net Zero a different way – with a greener concrete. The CEO and Co-founder of Sphera has developed a lightweight carbon negative additive using waste plastics that aren’t currently being recycled. She says the company’s blocks are the same strength and price as existing concrete blocks, but with 30% more thermal insulation. There is also the added benefit of reusing waste materials that would otherwise have gone to landfill or been incinerated.
Another solution discussed by Dominic Smith, Process Development Engineer at GSK, reduces energy consumption through green chemistry. He is trying to find greener ways to make medicines using enzymes. These enzymes, which can be found in plants and soil, replace chemical synthesis steps to cut energy consumption during processing and reduce hazardous waste.
Panel (left to right): Dominic Smith, Natasha Boulding, Clare Rodseth, Jake Coole, Nikita Patel, and Oliver Ring (Brett Parkinson spoke via video link).
It was apparent from the discussion that many solutions will be needed for us to reach our climate change targets. On the one hand, Jake Coole, Senior Chemist in Johnson Matthey’s Fuel Cells team, is working on membrane electrode assembly for hydrogen fuel cells to help us transition to hydrogen-powered buses and trucks.
At the same time, Clare Rodseth, an Environmental Sustainability Scientist at Unilever, has been using lifecycle assessments to reduce the environmental impact of some of the 400 Unilever brands people use all over the world every day. For example, this work has helped the company move away from petrochemical ingredients in its home care products. ‘Even small changes,’ she said, ‘have the potential to bring about large-scale change.’
Incremental change
However, for each of the technologies discussed, barriers remain. For Coole and co., having a readily available supply of hydrogen and charging infrastructure will be key. And for Dominic Smith and his colleagues, the use of enzymes in green chemistry is still in its infancy; and getting enzymes that are fast enough, stable enough, and produce the right yield is difficult. Nevertheless, he noted that manufacturers are now using enzymes to produce the drug amoxicillin, reducing the carbon footprint by about 25%
And some things will take time to change. Natasha Boulding noted that concrete is the second most used material in the world after drinking water, and we simply can’t create many green technologies, such as wind turbines, without concrete foundations.
She said the construction industry is quite traditional but also pointed to perceptible change, with the green concrete market growing and companies becoming increasingly aware of their carbon footprints.
Collaboration was seen as crucial in producing climate change solutions.
The reality is that global action on climate change is recent. As Brett Parkinson said: ‘the main reason we’re talking about it now is that there’s a driver to do it. Until the last decade, the world hadn’t cared about CO2 emissions. They just talked about caring about it.’
How pivotal is science in all of this?
So, what could be done to make climate action more effective? For Parkinson, effective policy is key. He argued that if the market isn’t led by policies that encourage low-carbon innovations, then it won’t work as needed. ‘It all starts with effective decarbonisation policy,’ he said. ‘Legacy industries are very resistant to change. If you don’t have strong and consistent policies… then they’re not going to adapt.’
Another key to our low-carbon evolution is collaboration, and the SCI provides a confluence point for those in industry and academia to work together to produce innovative, low-carbon products. As Clare Rodseth said: ‘Collaboration is really important – linking up people who can actually come together and address these problems.’
As the discussion came to a close, you had the impression that the debate could have gone on for much longer. ‘Hopefully, we’ve demonstrated that there is action, and it’s being driven by young people like our panellists today,’ summarised Oliver Ring, the event’s co-Chair, before asking for the result of the audience poll.
The question: How many of those watching believed that science is pivotal in providing climate change solutions?
The answer: Just the 100%.
>> Thank you to Johnson Matthey for sponsoring the event, to the speakers for sharing their time and expertise, and to co-chairs Nikita Patel and Oliver Ring for doing such an excellent job.
This Thursday at COP26, an inspiring panel of young scientists will discuss innovations that will help us mitigate climate change. So, what can we expect?
Millions of young people are frustrated by climate change inaction. Indeed, according to a University of Bath study, 60% of the next generation feel overwhelmed by climate anxiety. Often, the proposed solutions seem vague and intangible – well-intentioned ideas that drift away when the political winds shift.
And yet, when you see the ingenuity of young scientists, business people, and activists, it’s hard not to be excited. Undoubtedly, politics and our legal system will play a huge role in the drive to reach Net Zero, but arguably science will play the biggest role in transforming the way we live. Just think of the falling cost of generating solar power, improvements in battery chemistry for electric vehicles, the development of sustainable construction materials, and the rapid rollout of Covid-19 vaccines.
Tangible solutions
This Thursday at COP26, SCI will host the Next Gen youth forum event where the panellists discuss the climate change solutions they are working on right now and how they are being applied by industry. In the Countdown to Planet Zero roundtable, these scientists – drawn from within SCI’s innovation community – will explain their work to a global audience and the impact it will have on climate change.
They will discuss innovation in three key areas: topics of fuels of the future, turning waste into gold, and engineering nature.
The next generation has mobilised and is creating solutions to help avoid climate change disaster.
The panel will be chaired by two very capable young scientists. Oliver Ring is Senior Scientist at AstraZeneca’s large-scale synthesis team and Chair of SCI’s Young Chemists’ Panel, and passionate climate advocate Nikita Patel is a PhD student at Queen Mary University of London’s Centre of Translational Medicine and Therapeutics and STEM Ambassador for schools.
The other panel members include Clare Rodseth, of Unilever’s Environmental Sustainability Science team, who brings lifecycle analysis to product innovation to make products more sustainable.
Jake Coole, Senior Chemist in Johnson Matthey’s Fuel Cells team, is involved in the scale-up of new processes and next generation manufacturing, and Dominic Smith, Process Development Engineer at GSK, who is interested in engineering biology to create sustainable manufacturing processes.
Also present will be Dr Brett Parkinson, Senior Engineer of Low Carbon Fuels and Energy Technologist at C-Zero – a California-based startup that works on the decarbonisation of natural gas. In 2019, Brett was awarded an SCI scholarship for his research.
The lineup also includes Dr Natasha Boulding, CEO and Co-founder of Sphera Limited, a speciality materials company that has created carbon negative concrete blocks made from aggregate including waste plastic. According to Natasha, whose company also won SCI’s Bright SCIdea challenge in 2019: “In terms of combating climate change, interdisciplinary collaboration is the key. No one discipline has the answer to solve our biggest challenges – but together diverse minds can.’
>> Would you like to take part in BrightSCIdea and be in with the chance of winning £5,000? Be part of it.
Watch the event online
SCI is proud to be associated with these enterprising young scientists and the imaginative solutions they are developing to mitigate the effects of climate change.
‘As a global innovation hub, SCI wants to show how the next generation of scientists is actively developing solutions,’ said Sharon Todd, SCI CEO.
Sharon Todd, SCI CEO
‘Our COP26 youth forum debate will profile the work of young scientists and entrepreneurs addressing climate change in their work. This next generation of innovators has the power to change our world’s tomorrow.’
If you’d like to see the climate change solutions of tomorrow, register to watch the virtual event here.
Life is busy for Rhys Archer. Outside of her work as EPSRC Doctoral Prize Fellow in Biomedical Materials at the University of Manchester, she founded Women of Science to share stories about real women working in science. She has championed STEM in schools in her spare time and received the Robert Perrin Medal from the Institute of Materials, Minerals, and Mining – all before her 30th birthday.
Rhys is also refreshingly forthright in her views. She took the time to speak to us about everything from attitudes towards disability in academia, the problem with STEM statistics, and finding that sense of belonging in science.
Would you mind telling me about your work at the University of Manchester and the research areas that interest you most?
My research interests have always been interdisciplinary – I am a bit of a magpie when it comes to research and I get excited by projects in different areas. Luckily, being a researcher in materials science means that I can apply my knowledge and skills in a wide array of areas and industries. I have recently finished my doctoral studies looking at how carbon fibre composites are damaged during impacts, and how to toughen them while keeping composites light weight, which is particularly useful in the aerospace industry. However, I have since moved over to research in biomedical materials, specifically within tissue engineering, where I am researching biocompatible composite scaffolds for tissue regeneration.
You set up Women of Science in 2016 to share stories about real people in science. How has this been?
When I set up Women of Science, I first looked at it as a personal project that could be of use in schools to young people. However, it became apparent fairly quickly that access to relatable role-models in STEM was needed, not just in schools but also for women across the STEM industry.
Since then, we have been fortunate to be awarded funding to grow the work we do and expand our audiences. One of the most important actions I have taken with Women of Science is to set up an advisory board (which includes a diverse range of women) to share ideas and to influence the direction and activities of Women of Science.
As well as the impact on others, Women of Science has had a huge impact on me personally. When I set up Women of Science I was going through a difficult period of feeling isolated, and found it difficult to feel a sense of belonging in science and in research. By reaching out and hearing other women’s stories – not just their achievements, but also their doubts, worries, and difficulties – I found that I did belong in STEM. I just had to search for it.
Would you mind sharing some of the successes and challenges you’ve experienced in your own career?
At 29, towards the end of my PhD, I was diagnosed as autistic. Looking back, I can see that the challenges I faced, particularly because of depression, anxiety, and isolation, were due to my needs not being considered or met. Being disabled in academia is an ongoing challenge. It is still a fight to gain equitable working arrangements, opportunities, and acceptance.
However, I can also see how the successes I have had, such as setting up Women of Science, and being a part of other projects are a result of ‘being different’. My strongest quality is a diversity of perspective and experience and an eagerness to be a part of a range of different projects.
>> We’re keen to hear diverse perspectives from people working in the chemical industry. Get in touch with us at: eoin.redahan@soci.org
You have championed inclusivity in STEM. Do you think academic institutions and other workplaces could be more inclusive?
Yes. I think there is a huge amount of awareness and conversation about inclusivity in academia and industry, but not nearly as much action and intervention. Often I see workplaces with inclusive policies, but with little consideration of monitoring, evaluating, or reconsidering those policies. We must move past equity, diversity, and inclusivity being a checkbox exercise. The issues faced by women in the workplace are intersectional and complex, and so require well considered, complex solutions.
According to WISE, women now make up 24% of the STEM workforce in the UK. It estimates that this number could rise to 29% by 2030. What do you think about these figures?
While the number of women in STEM is a common metric when considering equality, this does not accurately portray issues surrounding inclusion and belonging. How are women treated? Do they have the opportunity to advance? Are there equitable policies and measures in place? This is particularly true of women in STEM who identify with other protected characteristics around race, disability, sexual orientation, and class. Once you dig into the statistics (where available) further, it is clear that the numbers given are not sufficient to describe the current situation for all women in STEM.
Also, the ‘leaky pipeline’ model is often considered, that is, that the number of women in STEM fall as we follow the statistics from school, to university, and onto the workplace. However, what is not always considered is that, as with a leaky pipeline, when more women are added, rather than ‘fixing’ the pipeline, the cracks become more obvious. Eventually, we reach a point when the pipeline is fractured. We must focus on repairing these cracks, not just increasing a numerical metric.
Additionally, in this current climate, it is incredibly difficult to make predictions as to what the future holds for the number of women in the STEM workforce. A couple of years ago, we could not foresee the impact that a global pandemic would have on women. When we consider the possible effects of climate change over the next decade, can we predict the burden that will be placed on women, or how this will affect women’s choices?
What’s next for you? Are you involved in any exciting projects?
With Women of Science, we have three projects that will be launched towards the end of the year, including a new website, flashcard activities for young people, and a report on the impact of the pandemic on women in STEM. Further ahead, I would love to expand the reach of Women of Science further, working with podcasting and film, as well as reaching out to policy makers. Personally, I am excited to get my teeth stuck into a new research project and see where that leads, as well as doing more teaching, consulting, and any other opportunities that come my way!
>> Are you interested in getting involved in Women of Science? Visit: www.womenofsci.com
Which technologies will propel industry forward and give companies that competitive advantage? According to digital consultancy McKinsey Digital’s Tech Trends Index, several technologies will have a profound and disruptive impact on industries including the chemical sector. So, which ones will have the biggest effect on the way you work in the coming decade?
By 2025, more than 50 billion devices around the world will be connected to the Industrial Internet of Things (IIOT) and about 600,000 industrial robots a year will be in place from 2022. The combination of these, along with industrial processes such as 3D and 4D printing, will speed up processing and improve operational efficiency.
According to McKinsey, 50% of today’s work practices could be automated by 2022 as ever more intelligent robots (in physical and software form) increase production and reduce lead times. So, how does this change look in the real world?
According to the McKinsey Tech Trends Index, 10% of today’s manufacturing processes will be replaced by additive manufacturing by 2030.
According to the Tech Trends Index, one large manufacturer has used collaborative robots mounted on automatic guided vehicles to load pallets without human involvement, while an automotive manufacturer has used IIOT to connect 122 factories and 500 warehouses around the world to optimise manufacturing and logistics, consolidate real-time data, and boost machine learning throughput.
An almost incredible 368,000 patents were granted in next generation computing in 2020. Advanced computing will speed up the processing of reams of data to optimise research and cut development times for those in the chemicals and pharmaceuticals industries, accelerate the use of autonomous vehicles, and reduce the barriers to industry for many eager entrants.
‘Next-generation computing enables further democratisation of AI-driven services, radically fast development cycles, and lower barriers of entry across industries,’ the index notes. ‘It promises to disrupt parts of the value chain and reshape the skills needed (such as automated trading replacing traders and chemical simulations, reducing the need for experiments).’
According to McKinsey, AI will also be applied to molecule-level simulation to reduce the empirical expertise and testing needed. This could disrupt the materials, chemicals, and pharmaceuticals industries and lead to highly personalised products, especially in medicine.
It doesn’t take much investigation before you realise that the bio-revolution has already begun. Targeted drug delivery and smart watches that analyse your sweat are just two ways we’re seeing significant change.
The Tech Trends Index claims the confluence of biological science and the rapid development of AI and automation are giving rise to a revolution that will lead to significant change in agriculture, health, energy and other industries.
In the health industry, it seems we are entering the age of hyper-personalisation. The Index notes that: ‘New markets may emerge, such as genetics-based recommendations for nutrition, even as rapid innovation in DNA sequencing leads ever further into hyper personalised medicine.’ One example of this at work in the agri-food industry is Trace Genomics’ profiling of soil microbiomes to interpret health and disease-risk indicators in farming.
It’s no secret that we will need to develop lighter materials for transport, and others that have a lighter footprint on our planet. According to McKinsey, next generation materials will enhance the performance of products in pharma, energy, transportation, health, and manufacturing.
For example, molybdenum disulfide nanoparticles are being used in flexible electronics, and graphene is driving the development of 2D semiconductors. Computational materials science is another area of extraordinary potential. McKinsey explains: ‘More new materials are on the way as computational-materials science combines computing power and associated machine-learning methods and applies them to materials-related problems and opportunities.’
5G networks will help take autonomous vehicles from tentative - to widespread use.
So, which sorts of advanced materials are we talking about? These include nanomaterials that enable more efficient energy storage, lighter materials for the aerospace industry, and biodegradable nanoparticles as drug carriers within the human body.
These are just four of the 10 areas explored in the fascinating McKinsey Digital’s Tech Trends report. To read more about the rest, visit: https://www.mckinsey.com/business-functions/mckinsey-digital/our-insights/the-top-trends-in-tech