2 April - 4 April 2025

41st SCI Process Development Symposium

Organised by:

Churchill College, Cambridge, UK

Prices start from £395.00

Early bird offer ends 27 January 2025

Synopsis

Process Development is the application of chemistry to the scale up of new synthetic processes from the laboratory, through pilot plant to full scale commercial manufacture and into life cycle management. It is an extremely broad discipline, crossing the boundaries between synthetic organic chemistry, process technology and chemical engineering.
The area of Process Development continues to be a challenging and important area for the research into and application of modern synthetic organic chemistry, as well as enabling technologies.

Attendees

The symposium aims to bring together a wide range of speakers from across the Pharmaceutical, Agrochemical and Fine Chemical industries, as well as from an academic background. This meeting brings together experts from across the entire spectrum of the discipline to present state of the art process development.

Sponsorship information

For further information and prices, please email conferences@soci.org.

Accommodation

En-suite accommodation can be booked for delegates at the college. Bedrooms will be allocated on a first come, first served basis. The accommodation package is for 2 nights – Wednesday 2 and Thursday 3 April and includes full English or Continental breakfast plus an evening meal on Wednesday 2 April. Rooms must be vacated by 10.00am on the day of departure. Luggage storage will be made available on the day of departure.

Please note: Bedrooms at the college will be available from 14:00 on the day of arrival.

Those not wishing to stay in college accommodation can book accommodation directly through www.visitcambridge.org

Programme

Wednesday 2 April

11.00: Registration and refreshments (buttery)
12.15: Lunch and exhibition (dining hall and buttery)

CHAIRPERSON: Dr Hilmar Weinmann, Johnson & Johnson Innovative Medicine, Belgium

13.25: Opening remarks
13.30: Process chemistry and catalysis @ Roche - Capabilities and case studies
Dr Stefan Hildbrand, F. Hoffmann-La Roche Ltd, Switzerland
14.10: Fact or fiction: Solid-phase peptide synthesis with reduced environmental impact and increased productivity
Dr Daniel Sejer Pedersen, Novo Nordisk, Denmark
14.50: Process safety hazard assessments strategy at R&D: from the lab to the plant
Dr Albert Colomer, UCB Pharma S.A., Belgium
15.30: Refreshment break and exhibition (buttery)

CHAIRPERSON: Dr Matt Burns, AstraZeneca, UK

16.10: Process development for the manufacture of a topical pan-Trk inhibitor incorporating decarboxylative sp2-sp3 cross-coupling
Dr David Fengas, Concept Life Sciences and Dr Neil Stevenson, Benevolent AI, UK
16.50: Will chemical AI and robots take our jobs?
Prof Bartosz Grzybowski, IBS Center for Algorithmic and Robotized Synthesis, S. Korea
17.30: Closing remarks
17.35: Wine reception sponsored by ChiralQuest (until 18.15) (buttery)
19.00: Dinner for residents of the college – tickets required (dining hall)

Thursday 3 April

CHAIRPERSON: Dr David Lathbury, Astute chemical development consulting Ltd, UK

09.00: The largest small molecule: The manufacturing process for Enlicitide Decanoate
Dr David Thasivongs, MSD, USA
09.40: Deploying continuous manufacturing technologies for the production of API’s
Dr Steven Raw, Asymchem Labs, UK
10.20: Refreshment break and exhibition (buttery)

CHAIRPERSON: Dr Richard Horan, GSK, UK

10.50: Transitioning from palladium to nickel catalysis for miyaura borylation and suzuki-miyaura cross-coupling reactions
Dr Henrique Esteves, BMS, UK
11.30: Case study
Dr Sarah Cleary, HydRegen, UK
12.10: Lunch and exhibition (dining hall and buttery)

CHAIRPERSON: Dr Hazmi Tajuddin, Syngenta, UK

13.10: Predicting your process: How system modelling accelerates understanding in process chemistry
Sophie Duffield, GSK, UK
13.50: The autocatalytic decomposition of nitro-containing species: New Insights to assist safe process development
Dr Alex Gaywood, Syngenta, UK
14.30: Synthesis of Bersacapavir: route scouting effort and scale up challenges of a new and innovative haloform-type amidation
Dr Florian Medina, Johnson & Johnson Innovative Medicine, Belgium
15.10: Refreshment break and exhibition (buttery)

CHAIRPERSON: Dr Irene Giménez-Nueno, GSK, UK

15.40: Recent examples of Flow technology at Lonza
Dr Simon Wagschal, Lonza, UK
16.20: Process chemistry award winner 2025
to be announced in January 2025
17.20: Closing remarks
17.30: Wine reception sponsored by Lonza (until 18.15) (buttery)
19.00: Symposium dinner – tickets required (dining hall)

Friday 4 April

CHAIRPERSON: Dr Max Espensen, Pharmaron, UK

09.00: Evolve flow chemistry into liquid phase peptide synthesis technology
Dr Eric Fang, Cambrex, UK
09.40: Kinetic and reaction engineering approaches for chemical process development
Dr Suju Mathew, Matheus Engineering, UK
10.20: Refreshment break and exhibition (buttery)

CHAIRPERSON: Dr Rob Walton, Asymchem, UK

10.50: Synthesis and Process Development of an Antiviral Drug – a Multi-kg Case Study
Dr Dide Verhoeven, Symeres, The Netherlands
11.30: Risk and reward: striking a balance for early campaign deliveries
Dr Peter Lindsay-Scott, AstraZeneca, UK
12.10: Close

Accessibility Grants

SCI accessibility grants are available to support SCI members with disabilities, long term health conditions, those who require a carer, and members who are nursing parents to attend SCI events. Download an application form to apply for a grant.

Venue and Contact

Churchill College

Storey's Way
Cambridge
CB3 0DS

Conference Team

Tel: +44 (0)20 7598 1561

Email: conferences@soci.org

Fees

Early bird- ends Monday 27 January 2025
SCI Member - £395
Non-member - £450
SCI Member with ensuite accommodation - £652
Non-member with ensuite accommodation - £707

After early bird
SCI Member - £520
Non-member - £575
SCI Member with ensuite accommodation - £777
Non-member with ensuite accommodation - £832

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Booking Process/Deadlines

Booking terms and conditions

CPD Info

SCI Members attending this meeting are able to claim CPD points.

Gold Exhibitor

Silver Exhibitors

Almac
SpiroChem AG
Chiral Quest

Bronze Exhibitors

Navin Molecular
ABCR UK Ltd
CatSci
Stoli Catalysts
Bellen Chemistry
Cambrex
Matheus Engineering

Organising committee

Max Espensen, SCI/Pharmaron
Richard Horan, SCI/GlaxoSmithKline
Dave Lathbury, SCI/Astute Chemical Development Ltd
Hazmi Tajuddin, Syngenta
Robert Walton, Asymchem
Hilmar Weinman, Janssen Pharmaceutical Companies of Johnson & Johnson