11 June 2025
New modalities: Innovations in RNA therapeutics
Organised by:
SCI’s Fine Chemicals group
SCI, London, UK
Synopsis
The recent advancements in RNA modulators with multiple mechanisms of action (MOAs) has unlocked a plethora of new biotherapeutics to target previously undruggable pathways.In addition to therapeutics that directly target RNA binding, there have also been recent advances in discovery of RNA epigenetics, splicing modulators and modulators of transcription/translation. RNA degradation by RiboTACs or RiboSNAPs is also opening significant innovative opportunities in this complex and expanding research area.
The SCI “New modalities” series comprises focussed in-person events and this year’s symposium brings together world-class scientists at the forefront of RNA research.
Attendees
This event is for academic and industrial scientists interested in insights into the challenges posed and potential for RNA biotherapeutics to make a real-world impact, plus networking with active researchers in this space.
Programme
Wednesday 11 June
- 10.00
- Registration and refreshments
Session 1
- 10.40
- Welcome and opening remarks
- 10.45
- Post-transcriptional regulations by small molecules targeting RNA-binding proteins
Dr Peng Wu, Chemical Genomics Centre of the Max Planck Society, Germany - 11.25
- Visual biology approach to discover compounds which modulate proteins that regulate mRNA biology
Dr Iris Alroy, Anima Biotech, Israel - 12.05
- Lunch, exhibition and posters
Session 2
- 13.15
- Hit discovery for riboswitches
Prof Ruth Brenk, University of Bergen, Norway - 13.55
- Targeting RNA methyltransferases: hit finding to candidate delivery
Dr Beth Thomas, Storm Therapeutics, UK - 14.40
- Refreshments, exhibition and posters
Session 3
- 15.10
- Development of a novel resource for assessing RNA folding and function to accelerate target assessment
Dr Giuseppina La Sala, AstraZeneca, Sweden - 15.50
Speaker to be confirmed- 16.30
- Sequence-based design of small molecules targeting RNA
Prof Matt Disney, UF-Scripps, USA - 17.20
- Networking reception
Accessibility Grants
SCI accessibility grants are available to support SCI members with disabilities, long term health conditions, those who require a carer, and members who are nursing parents to attend SCI events. Download an application form to apply for a grant.
Exhibition and sponsorship information
Please see the sponsorship pack and email conferences@soci.org to let us know which package you are interested in.
Call for poster abstracts
Opportunities are available for a limited number of posters. Interested applicants should send an abstract of maximum one A4 page or 300 words, indicating title and authors to, conferences@soci.org by Friday 2 May 2025 with the subject line “New modalities – poster submission”. Please download an SCI_Abstract_Template.
Venue and Contact
SCI
14/15 Belgrave Square
London
SW1X 8PS
Conference Team
Tel: +44 (0)20 7598 1561
Email: conferences@soci.org
Fees
Before early bird - ends Friday 9 May
SCI Member - £75
Non-member - £130
SCI Student member - £42
After early bird
SCI Member - £125
Non-member - £180
SCI Student member - £67
All registrations will automatically receive a confirmation within 24 hours of registering for the event. Should you not receive written confirmation of your booking, please email conferences@soci.org.
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Booking Process/Deadlines
CPD Info
All delegates attending this meeting are able to claim CPD points.
Exhibitors
Sponsors
Organising committee
Mark Frigerio, Bicycle TherapeuticsHelen Horsley, UCB
Caroline Low, Isomorphic Labs
Sarah Major, Dark Blue Therapeutics
Jason Tierney, MedChemica