14 October 2014

Highlights in Medicinal Chemistry

Organised by:

SCI’s Fine Chemicals Group

SCI, London, UK

Registration Closed

This event is no longer available for registration.

Synopsis

This meeting aims to showcase vignettes of modern medicinal chemistry to bring new thinking to the subject, challenge perceptions and encourage scientific interaction between researchers. The short presentation format of the meeting also aims to provide a focussed forum to promote examples of medicinal chemistry excellence.

Attendees

This meeting is targeted at academic and industrial scientists engaged in all aspects of the drug discovery process and those interested in broadening their knowledge at the forefront of medicinal chemistry.

Programme

Day 1

09:20: Registration and refreshments
09:50: Welcome and introduction
09:55: Data mining ChEMBL for new leads against new targets
Dr John Overington, European Molecular Biology Laboratory - European Bioinformatics Institute (EMBL-EBI)
10:35: Fatty Acid Synthase (FAS) triazolone inhibitors, good potency & properties but a metabolic liability?
Dr Cliff Jones, AstraZeneca
11:00: Stabilised receptor enabled structure based drug design: Identification of dual orexin receptor antagonists (DORAs)
Dr Sarah Aves, Heptares
11:25: Refreshments
11:45: Squaramides: physical properties, synthesis & application in medicinal chemistry
Dr Ian Storer, Pfizer
12:10: Fragment-based drug discovery for a protein-protein interaction target: from mM fragments to nM dual antagonist of XIAP and cIAP1
Dr Emiliano Tamanini, Astex
12:35: The monster mas agonist - revealing the beauty in the beast
Dr Simon Peace, GlaxoSmithKline
13:00: Lunch and exhibition
14:00: A tale of two MEK inhibitors - the difficulty of preclinical differentiation
Dr Henrik Moebitz, Novartis
14:25: Structure-guided design of BH3-mimetic Mcl-1 inhibitors
Dr Jonathan Hollick, Evotec
14:50: Dr Lilian Alcaraz, Argenta
15:30: Refreshments
15:50: Designing membrane permeable 'large' molecule NS5A inhibitors
Dr David Pryde, Pfizer
16:15: Discovery of ATR selective inhibitors for the treatment of cancer
Dr Joanne Pinder, Vertex
16:40: Matched triplicates in the optimisation of a novel series of glucokinase activators
Dr Mike Waring, AstraZeneca
17:20: Closing remarks
17:25: Wine reception

Accessibility Grants

SCI accessibility grants are available to support SCI members with disabilities, long term health conditions, those who require a carer, and members who are nursing parents to attend SCI events. Download an application form to apply for a grant.

Venue and Contact

SCI

14/15 Belgrave Square
London SW1X 8PS

Conference Team

Tel: +44 (0)20 7598 1561

Email: conferences@soci.org

Fees

Early Bird Rate - before 29 August 2014

One-Day Fee		Two-Day Fee*
SCI Member	GB£100	SCI Member	GB£175
SCI Student Member	GB£35	SCI Student Member	GB£60
Non-Member	GB£130	Non-Member	GB£235

Standard Rate - after 29 August 2014

One-Day Fee		Two-Day Fee*
SCI Member	GB£115	SCI Member	GB£205
SCI Student Member	GB£40	SCI Student Member	GB£70
Non-Member	GB£150	Non-Member	GB£270

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Booking Process/Deadlines

Booking terms and conditions

CPD Info

SCI Members attending this meeting are able to claim CPD points.

Third Tier Sponsor/Exhibitors

Additional Info

Exhibition and Sponsorship

An exhibition will take place alongside the conference for companies and related organisations who may wish to exhibit. Please email conferences@soci.org for further information and prices. Spaces are limited and will be allocated on a first-come, first-served basis.