Journal of Chemical Technology & Biotechnology

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An international peer-reviewed journal concerned with the application of scientific discoveries and advancements in chemical and biological technology

The Journal of Chemical Technology and Biotechnology is an international peer-reviewed journal concerned with the application of scientific discoveries and advancements in chemical and biological technology that aim towards economically sustainable industrial production or are necessary for environmental protection. JCTB focuses on the interfaces between chemical technology and biotechnology, especially where these impact on health and safety and the environment. The journal features reviews, research articles, and technical notes. Journal of Chemical Technology & Biotechnology on Wikipedia

Readership

Researchers in the fields of

Process and Environmental Technology
Biotechnology
Biochemistry
Chemistry
Chemical Engineering

Related themes

Health & Wellbeing

Countering drug resistance, developing new medicines and pioneering treatments such as immunotherapy and CRISPR.

Environment

Sustainability & Environment

Advancements in resource efficiency and progress towards a circular economy are at the core of sustainable innovation.

Science & Innovation

Facilitating collaboration between multidisciplinary scientists, investors, lawyers, companies, institutions – the list goes on!

From the latest issue

Facile Design of Continuous Periodic Countercurrent, dual-flow, and capture SMB adsorptive processes

Chromatographic capture is a critical step in the manufacture of protein-based therapeutics and often dominates the overall downstream processing cost. Multicolumn systems as well as systems where the load flow rate varies over time can be used to improve productivity and reduce the consumption of buffers and other process chemicals by enhancing utilization of the binding capacity. This work addresses the design of such systems under mass transfer control conditions using a mechanistic model. The results cover the ranges typically encountered in the capture of biopharmaceuticals with selective adsorbent particles and can be used for practical estimations. This work will allow the rapid design of periodic countercurrent, dual-flow capture systems, and capture SMB units and assessment of their relative advantages under varying operating conditions circumventing the need to perform computationally intensive simulations.

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